DIMACS 2015

## Albert Kuo

office: | CoRE 434 |
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school: | The University of Chicago |

e-mail: | albertkuo@uchicago.edu |

project: | Development of machine learning algorithms in biology |

#### The Project

DIMACS (the Center for Discrete Mathematics and Theoretical Computer Science) was founded as one of 24 Science and Technology Centers funded by the NSF. It hosts a 9-week REU program, which I attended in the summer of 2015.

I worked with Dr. Kevin Chen and explored epigenomic data for predicting enhancers -- sequences in the DNA that regulate gene expression. The machine learning algorithms I used included hidden Markov models (HMMs), support vector machines (SVMs), and logistic regression. I combined various datasets with these models to better understand the relationships between enhancer marks and their role in enhancer prediction.

#### Weekly Log

#### Links

- Program Info: DIMACS REU

- My mentor: Dr. Kevin Chen